life-threatening

Thirteen people in the United States have been infected with a potentially deadly, drug-resistant fungal infection since 2009, health officials say. [1] [2]
Source: CNN
Of those infected, 4 individuals died; but it is not clear whether they died from the infection or from other underlying health problems. [1]
Dr. Tom Chiller, who is chief of the mycotic diseases branch of the U.S. Centers for Disease Control (CDC), said:

“I am worried. I think this is a real threat.” [2]

A leading group of pediatricians said in a statement published September 19 that codeine is not safe for children and should not be used to relieve pain or coughs. [1]
The guidance nearly mirrors a January 2016 Food and Drug Administration (FDA) warning that codeine should not be given to children and most teens.