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The indications which are presented below are the guidelines which physicians working at IppocrateOrg Call Centre are currently referring to when treating Covid-19 patients.
We want to emphasise that drugs and supplements and their dosage are to be considered as a mere indication. The treating physician must determine and prescribe the appropriate therapy for each patient.
So NEVER without a doctor!
IMPORTANT NOTICE
Covid-19 is a complex syndrome for which a specific treatment has not been identified yet.
Our therapeutical approach is a personalised treatment, based on the available scientific evidence, on the biological plausibility and on each patient situation. The only purpose of this publication is not to give guidelines or therapeutical indications, but to open a dialogue between physicians to get a better treatment of the patients involved in this current pandemic.
All the published indications are for practitioners only.
In order to get the best ‘at home therapy’ for outpatients, basic guidelines proposed (updated to 27th March 2021) by IppocrateOrg, consider the progression of the disease in 3 stages, as they are well known from the majority of clinicians:
STAGEPATHOPHYSIOLOGYCLINIC
STAGE 1(Early Infection)
Virus replication
Flu-like symptoms (fever, joint and muscle pain, headache, weakness..)
STAGE 2(Pulmonary Phase)
Lung complication
Cough, dyspnoea, polypnoea
STAGE 2AW/out hypoxia
STAGE 2BWith hypoxia
STAGE 3(Hyperinflammation Phase)
Cytokine storm or hypercytokinemia
SARS, vasculitis, microembolism, microthrombosis, multi-organ failure
We define STAGE ZERO as a test-positive patient without symptoms.We suggest application of STAGE ZERO therapy to all close contacts.
The recovery from Covid is often very long. We propose the following treatments to shorten it.
Early treatment is the winning strategy
STAGE Zero(Asymptomatic and test-positive patient)
DRUGDOSAGECONTRAINDICATIONS
Vitamin D3
50.000 IU/day for 6 days (if not in prophylaxis)10.000 IU./day for 6 days (if in prophylaxis)And then 4.000 IU/dayWhile eating a greasy meal (for example at lunchChildren: 200 IU/Kg/day (until negative test)
Severe Chronic Kidney Insufficiency (CKD)Hypercalcemia
Vitamin C
From 1 g/day, in consideration of formulation
Severe CKD, deficit G6PD
Zinc picolinate
30-50 mg/day
Esperidine
100 mg/day
Quercetin
Up to 250 mg x 2/day
Lactoferrin
Up to 200 mg x 2/day
Bromexine
8 mg x 3/day
Pelargonium S.
> 12 y-o: 20 mg x 3/day for 7 days6-12 y-o: 13 mg x 3/day for 7 days
Hemorrhagic diathesisF.E in patient in treatment with blood thinners
Suffumigation
3 times/day
Hydrossitirosol and α-cyclodestrine
2-3 puffs x 3-4/day in the throat
Other active ingredients known for their antiviral action
Vitamin A
Up to 30.000 IU/day
Pregnancy
Resveratrol
Up to 1000 mg/day
The proper combination of medications from the list will be prescribed by the physician, according to the patient’s needs and characteristics.
Our indication – in any case – is to prescribe: ✔ Vitamin D ✔ Zinc ✔ Vitamin Cwhich we recommend to be prescribed even in severe stages of the disease.
Hence if the patient is treated in stage 1 or 2, do not forget about prescribing these supplements in conjunction with the other drugs.
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STAGE 1(flu-like symptoms)
DRUGDOSAGECONTRAINDICATIONS
ASA
Up to 100 mg/day till asymptomatic
Ivermectine
0,2 mg/Kg of Body weight, maximum PC 18 mg2ª dose after 48 hours3ª dose (eventually) 48 hours after
Hydroxychloroquine (HCQ)
200 mg x 2/day for 7 days
Arrhythmias,RetinopathyDef. G6PDH
AzithromycinorDoxycycline
500 mg/day for 3 days, stop 2 days, then repeat
LQTS
100 mg x 2/day for 7 days
Colchicine
0.5 mg x 2/day for 14 days
Cardiac Insuff., CKDdo not use with Clarithromicin
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STAGE 2A(lung complication without hypoxia)
DRUGDOSAGECONTRAINDICATIONS
Montelukast
10 mg 2 hours after dinner for 14 days
Amoxi/Clavulanic acidorOther antibiotics
875 mg+125 mg x 3/day for 8-10 days
In association with Azithromycin in case of superinfection
Acetylcysteine
600 mg up to x 3/day fro 7 days
Levodropropizine
60 mg as needed, up to x 3/day
Enoxaparin
4.000 IU x 1-2/day for 10 days if weight < 70 Kg6.000 IU x 1-2/day for 10 days if weight 70-100 Kg
Hemorrhagic diathesisThrombocytopenia
N.B.: Practitioner will evaluate if patient will need corticosteroid on therapy as in stage 2B.
It is advisable to do thoracic ecography and/or ct scan
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STAGE 2B(lung complication with hypoxia)
DRUGDOSAGECONTRAINDICATIONS
O2-therapy
1-6 L/min if SpO2 < 92% in AA
Enoxaparin
100 IU/Kg/12 hours
Dexamethasone ⚠️
6 mg/morning OR 3 mg x 2/day
● do not associate but use alternatively● associate gastroprot.
Betamethasone ⚠️
8 mg/morning OR 4 mg x 2/day
Methylprednisolone ⚠️
32 mg/morning OR 16 mg x 2/day
Prednisone ⚠️
40 mg/morning OR 20 mg x 2/day
Deflazacort ⚠️
30 mg x 2/day
Antibiotics
According to practitioner’s judgment
Corticosteroids: NEVER AT THE BEGINNING, but only at the end of the viral stage!!● for 6-7 days then diminish● better one morning dose● 2 doses if patient is suffering (always Deflazacort, for its fast action)Contraindications: Hypertension, Hyperglycaemia, …
In case Oxygen > 6 L/min
or
SpO2 persistently < 92%
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HOSPITALISATION IS MANDATORY
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File Upload: Covid-19-home-treatment-updated-2021-03-27.pdf